APP and amyloidosis: In comparison to what has been reported for FBB PET with other mouse models of amyloidosis, these values are as high as those described for models with high FBB retention (homozygous PS2APP and APP-PS21 mice) and clearly superior to the single transgenic lines expressing only APPswe or Aβ42 (Rominger et al., 2013; Brendel et al., 2015; Waldron et al., 2015; Son et al., 2018).