NOTCH1 and colorectal carcinoma: The previous discussion showed that ALDH1 had been identified as a tumor cell marker [36], for instance, Christophe found that ALDH1 cell subsets had higher cancer stem cell characteristics [38], Mohamed identified that the expression of ALDH1 was highly correlated with the expression of Colorectal Carcinoma’s tumor stem cell markers Notch1 and CD44 [39], and we calculated the characteristic value of immune infiltration of UCEC patients through CIBERSORT and found that the change of ALDH2 was highly correlated with CD8+T cells.