Univariate analyses showed significant risk factors were CRP ≥ 1 mg/d (p = 0.005), peripheral arterial disease (p = 0.009), renal insufficiency (p = 0.023), operating time (p = 0.000), revision operation (p = 0.000), myocardial infarction within half a year before surgery (p = 0.027), transfusions ≥ 5 (p = 0.000) and the duration of intubation (p = 0.031). The gene discussed is CRP; the disease is Renal insufficiency.