Regarding STAT1, we observed a significant increase in CIN I, CIN II, and CIN III compared to Control for the two cell populations evaluated (CD4+ and CD8+) (p = 0.0350) (Figure 2B, C) in the CD8 + , STAT1+CD4+ (p = 0.0003); and STAT1 + CD8+ (p < 0.0001) populations. The gene discussed is CD8A; the disease is uterine cervix carcinoma in situ.