SNHG12-miR-181a-MAPK/Slug axis has been established in their research, and the role of lncRNA SNHG12 in NSCLC multidrug resistance (MDR) was partially elucidated, providing a new therapeutic target for the treatment of NSCLC MDR (Figure 3). This evidence concerns the gene SNAI2 and non-small cell lung carcinoma.