PER3 and BMAL1 (aka ARNTL) were differentially rhythmic between NGT and T2D donors (in total, six genes were shown to be differentially rhythmic between NGT and T2D donors; table S2) [Fig. 1E; both genes false discovery rate (FDR)DODR = 0.094]. This evidence concerns the gene BMAL1 and type 2 diabetes mellitus.