Gene expression levels for the adrenergic neuroblastoma CRC members—MYCN, HAND2, ISL1, PHOX2B, GATA3, ASCL1, and TBX2—were assayed by quantitative RT-PCR at 1, 3, and 6 days after treatment with 5 μM ATRA. This evidence concerns the gene ISL1 and neuroblastoma.