IFNA1 and Huntington disease: In HD, vaccination induced the generation of Spike-specific T-cells evaluated as Interferon gamma (IFN-ɣ) Colony Forming Units that significantly increased (from T0: median 2.5 SFU (IQR 0–0.69) to T1: 115 median SFU (IQR 0.13–5.25), P = 0.041).