In the case of KCNQ1OT1, its role in locally silencing the expression of the neighboring tumor suppressor cyclin‐dependent kinase inhibitor 1C (CDKN1C) may account for its oncogenic deregulation in cancers (Feng et al., 2018; Li et al., 2021; Wu et al., 2020). The gene discussed is KCNQ1OT1; the disease is cancer.