Notably, tumor-bearing AGS A-31 mice with a greater growth potential and tumor weight (Fig. S8E–G) demonstrated reduced EpCAM expression and exhibited a significantly increased content of stromal cell infiltration, as labeled with α-SMA (α-smooth muscle actin) or Col1a1 (collagen type I, alpha 1) antibodies compared to A-NTC cells (Fig. 6D, E). Here, COL1A1 is linked to neoplasm.