Interrogation of the DEG data set for interleukin (il) gene in AGD-affected gill identified multiple transcripts from nine il gene families whose expression was differentially expressed (Il-1β, Il-8, il-11, il-12 β, il-17 (a/d/f) il-18, il-27β, il-3) (Table 2). The gene discussed is IL1B; the disease is argyrophilic grain disease.