However, oral gavage of NK210 or NK219 suppressed LPS-induced colitis: they decreased myeloperoxidase activity, NF-κB+/CD11c+ cell population, and IFN-γ to IL-10 and TNF-α to IL-10 expression ratios in the colon while colon shortening was not significantly increased. The gene discussed is ITGAX; the disease is colitis.