It has been reported that curcumin and CurNPs can revert the aggravated serum lipid profile through lowering these secondary complications; obesity, adipogenesis, HMG-CoA reductase, cholesterol absorption, and intestinal transmission, lipogenic genes expression, raising LDL receptors and controlling some genes implicated in lipoprotein and lipid metabolism46,47. This evidence concerns the gene LDLR and obesity disorder.