KDM4D and nonpapillary renal cell carcinoma: KDM4D inhibition can also minimize migration of ccRCC cells, as demonstrated in Fig. 2B, C, the wound healing ability of the cells in the control group was significantly higher than that of the KDM4D-IN group (p < 0.001, Fig. 2B), and KDM4D significantly promotes the migration of kidney cancer cells (p < 0.001, Fig. 2C).