KDM4D and nonpapillary renal cell carcinoma: We treated 786-O and Caki-1 cells with 0.5 μm KDM4D inhibitor (KDM4D-IN-1, MedChemExpress LLC, New Jersey, USA) and performed colony formation assays in 10 cm dish, wound healing assays in 6-well plate, invasion and migration assays in Transwell to evaluate the effect of KDM4D on ccRCC proliferation and development.