PFKFB3 and cervical carcinoma: 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 enzyme (PFKFB3) and FBP are two glycolysis regulators upregulated in chemoresistant cervical cancer cells, and they increase glycolytic levels (exhibiting high glucose uptake, high ATP levels and low oxygen consumption rates) in cervical cancer cells [72].