Eight variables (mechanical ventilation, AKI, septic shock, creatinine level of > 1.13 mg/dL, urea > 7 mmol/L, ALT > 50 IU, AST > 50 IU, and platelet < 150 × 109/L) were found to be associated with severe illness in this study. The gene discussed is GPT; the disease is septic shock.