APOA1 and diabetes mellitus: The HDL/apoA-I-FT3-stratified risk factor interactions revealed that CAD risk in age < 55 years or non-DM with HDL-C/apoA-I ≤ 0.89 mmol/g and FT3 ≤ 4.5 pmol/L was stronger than those age ≥ 55 years or DM (Fig. 3A and B).