The importance of basolateral K+ channels is also reinforced by clinical data that identify loss of function mutations in KCNJ10 (Kir4.1) causing EAST/SeSAME syndrome, in which patients have hypokalemia, hypomagnesemia, and salt‐wasting (Celmina et al., 2019). Here, KCNJ10 is linked to Hypokalemia.