In permanent and primary human AML cells with and without FLT3-ITD, HDACi decrease RAD51, CHK1, and the cell cycle regulatory kinase WEE1 (Dai et al. 2013; Li et al. 2019a; Qi et al. 2015; Xie et al. 2013; Zhao et al. 2017; Zhou et al. 2015). This evidence concerns the gene CHEK1 and acute myeloid leukemia.