We incubated human AML cells with FLT3-ITD (MV4-11 cells, from a biphenotypic B myelomonocytic leukemia in a 10-year-old male child) with 1–5 nM AC220 and 1–5 nM FK228 for 24 h (36 conditions, 25 combinations of AC220 plus FK228). This evidence concerns the gene FLT3 and acute myeloid leukemia.