This leads to the aggravation of adult respiratory distress syndrome, which is present in around 15% of COVID-19 patients and responsible for generalized tissue damage, multiple organ failure, and death.[12] Poor prognostic factors identified in a study of 1449 hospitalized patients with COVID-19 included older age and elevated CRP, d-dimer, and lactate dehydrogenase levels, among others.[13]. The gene discussed is CRP; the disease is COVID-19.