ITPR1 and acute kidney injury: The highest scorings proteins associate with IP3-receptors in the ER, including: TMEM33 (p = 4.33E–06; log2FC = 20.46), a Ca2+ regulator affecting acute kidney injury [39, 40], ERLINs, which regulate IP3 receptors, DNAJs regulating degradation, and ARFs controlling G-protein coupled receptors (GPCRs).