The results showed that age (P = 0.0072), TNM stage (P = 0.0002), lymph node metastasis (P = 0.0012), ADAM12 expression (P = 0.0052), EDNRA expression (P = 0.0125), STC1 expression (P = 0.0086), and CPNE8 expression (P = 0.00081) were significantly related with the prognostic of GC patients (Table 2). This evidence concerns the gene CPNE8 and gastric cancer.