BCL2 and acute myeloid leukemia: As a benchmark and reference, we used the BCL-2 inhibitor ABT-199 (venetoclax)49, which is US Food and Drug Administration (FDA) approved, in combination with AZA or decitabine for the treatment of AML in adults of 75 years or older (https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-regular-approval-venetoclax-combination-untreated-acute-myeloid-leukemia).