In addition to evidence supporting the authors' behavioral hypothesis that girls were more likely to experience depressive symptoms in the setting of mismatched maternal prenatal–postnatal depression (in this case, either low prenatal depression followed by high postnatal depression, or vice versa), the results of their follow-up study showed that prenatal–postnatal mismatch had strong effects on NR3C1 methylation in girls only, with low prenatal depression followed by high postnatal depression resulting in the largest increase [263]. Here, NR3C1 is linked to postpartum depression.