CCN2 and non-small cell lung carcinoma: Others have found that NSCLC-CAFs respond to radiation by increased secretion of basic fibroblast growth factor (bFGF), growth arrest-specific protein 6 (GAS-6) and macrophage migratory inhibitory factor (MIF), but decreased CXCL12/SDF-1, connective tissue growth factor (CTGF) and IL-6 [104].