Then, we detected 5 abnormally expressed autophagy-related proteins that may be associated with the pathogenesis of ITP, among which 4 (HSPA8, PARK7, YWHAH, and ITGB3) were downregulated and 1 (CSF1R) was significantly upregulated in ITP patients compared with the controls. The gene discussed is ITGB3; the disease is autoimmune thrombocytopenic purpura.