By evaluating tumor volume (Fig. 5a), intratumoral green fluorescent protein (GFP) fluorescence (Fig. 5b, c), tumor size (Fig. 5d), and tumor weight (Fig. 5e), we found that SNTB1 knockdown significantly suppressed tumor growth of both HCT116 and RKO cells in vivo. The gene discussed is SNTB1; the disease is neoplasm.