EGFR and neoplasm: In training cohort A, through statistical analysis and in consideration of clinical significance, the presence/absence of concurrent genetic mutation (i.e., exclusive EGFR activating mutations, concurrent oncogenic driver gene mutation, or concurrent tumor suppressor gene mutation) and the location of metastasis (i.e., locally pleural, brain, or liver metastasis) were selected as the molecular and clinical factors to generate the nomograms for estimating the 12-month and 18-month PFS rates of T treatment (Fig. 4A).