Furthermore, the levels of TNF-α and IL-6 increased as nephropathy progressed, with median serum TNF-α levels of 13.49 pg/mL in the normoalbuminuric group, 15.22 pg/mL in the Micro-MA group, and 18.28 pg/mL in the Macro-MA group. The gene discussed is TNF; the disease is kidney disorder.