Two tumors harbored the activating p.V600E hotspot mutation in BRAF, three tumors harbored the activating p.N546K or p.K656E hotspot mutations in FGFR1, two tumors harbored activating hotspot mutations at codon p.Q61 in HRAS, and another tumor harbored a potentially pathogenic mutation in HRAS at p.P169. The gene discussed is HRAS; the disease is neoplasm.