Plasma GFAP levels were higher in individuals with MCI+ (128% increase; P < .001; d = 1.40) and in those with AD dementia (133% increase; P < .001; d = 1.37) compared with the CU– group, and no difference was found between the CU– group and non-AD group (Figure 1E). The gene discussed is GFAP; the disease is Alzheimer disease.