PFKFB3 and Sepsis: To examine the role of myeloid Pfkfb3 in LPS-induced cardiac dysfunction (one of the features of multi-organ dysfunction in sepsis), Pfkfb3WT and Pfkfb3ΔMφ mice were intraperitoneally administered with LPS, and cardiac assessment was used to record the cardiac parameters using M-mode echocardiography.