Exosomal miR-21 can inhibit the expression of the lncRNA-PTENp1 to promote HCC growth, miR-21 inhibitors or lncRNA-PTENp1 overexpression can weaken the role of exosomal miR-21, which indicates that PTENp1 can repress the tumorigenic properties of HCC cells (114). Here, PTENP1 is linked to hepatocellular carcinoma.