LncRNAMALAT1 induces murine HCC experimentally, H19 expression is upregulated in HBV-associated HCC, HOTAIR is overexpressed in tumor tissues from HCC patients and in liver cancer cell lines, and is related with poor prognosis of HCC, HBx upregulates lncRNAHULC by inhibiting P18 and promoting the occurrence of HCC (103, 105, 107, 108). This evidence concerns the gene H19 and hepatocellular carcinoma.