VWA8 and scoliosis: Data from Allen Brain Atlas10 (in situ hybridization) also revealed a high level of vwa8 expression in the cerebellar granule cell layer.11 The presence of scoliosis phenotype in the vwa8 knockout mice supported the notion that VWA8 pathogenesis might cause defects in skeletal development and associated abnormalities, thus supporting the data presented here.