LGALS3BP has been found in diverse cancer-derived exosomes (Escrevente et al., 2013; Ung et al., 2014; Dutta et al., 2015; Gomes et al., 2015; Song et al., 2021), and APOE has been found in exosomes released from macrophages (Zheng et al., 2018) and neurons (Nikitidou et al., 2017; Mathews and Levy, 2019; Peng et al., 2019). The gene discussed is APOE; the disease is cancer.