Therefore, for an in vivo analysis of the role of recruited macrophages on L. amazonensis lesion evolution, we performed the adoptive transfer of macrophages (ATM) from partially resistant mice (C57BL/6) to susceptible ones (BALB/c) after 9 weeks of infection, the time point at which the paw edema starts to significantly differ between the mice strains (Figures 1A, 7A). This evidence concerns the gene ATM and infection.