CDCA2 and hepatocellular carcinoma: Moreover, the differences in survival time could not be well distinguished by applying TNM stage in the early HCC group (TNM stage I/II) or in the mid- to late-stage HCC group (TNM stage III/IV) (p > 0.05) (Figures 5B, C); however, CDCA2 could distinguish well the survival time of these two groups (p < 0.05) (Figures 5E, F).