Interestingly, an integrative analysis of metabolomics based on mass spectroscopy revealed differential expression of metabolites; association of AKT1 and MYC activation correlated with accumulation of metabolites of aerobic glycolysis and dysregulated lipid metabolism in human tumours, mouse models, and also in cultured cells (RWPE-1 cells), establishing the oncogene-associated metabolic signatures in PCa (27). Here, MYC is linked to neoplasm.