PTTG3P and colorectal carcinoma: To verify the expression of PTTG3P in CRC, we investigated the detailed annotative process of preclinical human cancer models via the Cancer Cell Line Encyclopedia (CCLE) (www.broadinstitute.org/ccle) and found that PTTG3P was remarkably overexpressed in CRC cell lines (Supplementary Figures 1E, F).