MST1 and neoplasm: In addition, we designed and carried out a series of rescue experiments, PTTG3P plus YAP1 knockdown partly reversed proliferation, apoptosis, and tumor growth induced by PTTG3P (Figures 4D–G); however, treatment with the Hippo pathway inhibitor, XMU-MP-1 (an inhibitor of MST1/2), barely induced any effects on these processes (Figures 4H–K).