It is known that proinflammatory cytokines promote tumor cell growth and invasion through activation of transcription factor NF-κB (18); therefore, we explored the expression and nuclear translocation of NF-κB associated with malignancy and survival of CRC cells and performed immunofluorescence labeling for p65-NF-κB as described in Materials and Methods. Here, NFKB1 is linked to neoplasm.