Compared with the non-lymph node metastasis group, the proportion of age <55 years, male, multiple foci, bilateral foci, diameter >0.5cm, extracapsular invasion, HT, and intermediate-to-high risk stratification for recurrence in lymph node metastasis group was significantly higher (all p<0.05), while the differences in BMI, BRAF gene mutation rate, distant metastasis, and TNM stage were not statistically significant (all p>0.05) (Table 2). The gene discussed is BRAF; the disease is metastatic malignant neoplasm in the lymph nodes.