This group described as “non-obese” NAFLD may have contributing risk factors including insulin resistance, weight gain within normal weight limits, visceral obesity, high cholesterol and fructose intake, genetic risk factors such as TM6SF2 and patatin-like phospholipase domain-containing protein 3 (PNPLA3) polymorphism [3, 5]. This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatotic liver disease.