The microtubule-stabilising protein superior cervical ganglion 10 (SCG10; also known as stathmin-2 [STMN2]) is a short-lived protein that is constantly supplied to the axon by fast axonal transport and is implicated in TDP-43 neuropathies, in particular ALS [173]. Here, STMN2 is linked to amyotrophic lateral sclerosis.