In addition, we used the TIMER database to determine the correlation between DVL-1 expression and genes expressed by different innate immune cells including monocytes, tumor-associated macrophages (TAM), M1/M2 macrophages, neutrophils, NK cells and dendritic cells in luminal, HER2-positive, and TNBC subtypes of breast cancer as summarized in Table 2 and Supplementary Figure 4. Here, ERBB2 is linked to breast cancer.