We found that there was an overlap of 6,240 genes and 74 genes altered in breast cancer patients and DVL-1 ChIP Seq hits in MDA-MB-231 and MCF7 cells respectively, which corresponds to 31% of DVL-1 hits in MDA-MB-231 and 0.4% of DVL-1 hits in MCF7 (Figure 3D–3E), further suggesting the importance of subtype-specific DVL-1 associations in patient tumors. This evidence concerns the gene DVL1 and breast carcinoma.