IRF6 and nonpapillary renal cell carcinoma: Thus, the DNA methylation data of 325 ccRCC tissues and 160 adjacent normal renal tissues from TCGA-KIRC was used to compare the methylation levels of 16 CpG sites (cg00989853, cg04352962, cg05034446, cg09509183, cg10074409, cg11570233, cg12034118, cg16030177, cg21851713, cg21951975, cg22029157, cg22338127, cg22442454, cg23283495, cg25192855 and cg25204440) of IRF6 DNA (Figure 4A), and the detailed information of these CpG sites was provided in Table 4.