For example, IRF6 predicts a favorable prognosis in gastric cancer 13; IRF6 distinctively reverses stemness phenotype in nasopharyngeal carcinoma 14; IRF6 downregulation promotes squamous cell carcinoma (SCC) cell invasive and reintroduction of IRF6 into SCC cells inhibits cell growth 15; miR-587 promotes cervical cancer by repressing IRF6 16. Here, IRF6 is linked to squamous cell carcinoma.