Univariate analysis indicated that patients with high level of FMNL1mRNA and CORO1A mRNA showed shorter overall survival (FMNL1 mRNA HR: 1.483, p<0.000; CORO1A mRNA HR: 1.279, p=0.001), while multivariate analysis indicated that only FMNL1 mRNA had negative prognostic value in ccRCC (HR: 1.210, p=0.036) (Table 2). The gene discussed is CORO1A; the disease is nonpapillary renal cell carcinoma.