Since we observed a decrease in EMT and migration in p68 knockdown cells upon PDGF-BB treatment, we sought to investigate the effects of p68 knockdown on PDGF-BB signaling, probing the levels of phospho-PDGFR-β in the p68 knockdown breast cancer cells upon PDGF-BB stimulation. The gene discussed is DDX5; the disease is breast carcinoma.