A schematic representation of the interplay among RNAs within the hsa_circ_0001306/miR-527/FBXW7 pathway is shown in Figure 7E. Our findings strengthen our understanding of the ceRNA mechanism of circRNAs in HCC progression, and hsa_circ_0001306 may be a potential biomarker for HCC diagnosis and treatment. The gene discussed is FBXW7; the disease is hepatocellular carcinoma.