We concluded that the signature risk score was mainly involved in tumor-infiltrating immune cells such as B cell, macrophage, macrophage M1, plasmacytoid dendritic cell, macrophage M2, cancer-associated fibroblast, CD8+ T cell, endothelial cell, neutrophil, stroma score, uncharacterized cell, NK cell, CD4+ T cell, and T cell follicular helper (Figure S1). The gene discussed is CD8A; the disease is cancer.