Patient 8 underwent genetic tests because of suspicious HPT/JT syndrome due to previous sarcoma and kidney carcinoma: CDC73, AIP, CDKN1B, GNAS, HRAS, MEN1, NF1, VHL, MAX, GPR101, PRKAR1a, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, EPAS1. The gene discussed is CDKN1B; the disease is renal carcinoma.